In episode 485, Mike and James go over a couple of COVID trials that show two different anti-inflammatories – colchicine and inhaled budesonide – seem to have an effect on reducing hospitalizations or urgent care visits. 1) Colchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded,… Read More
In episode 483, James and Mike invite Tina to the podcast to talk about the aducanumab (Aduhelm) FDA approval story. We look at all the latest evidence, we talk about how people analyzed the data, whether or not the findings were clinically important, the side effects and finally the cost. Read More
In episode 482, Mike and James take a look into all the evidence for baths for atopic dermatitis. The evidence is fairly clear that more frequent bathing has a reasonable effect in people with moderate to severe atopic dermatitis. However, adding bleach or anything else to the bath doesn’t seem… Read More
In episode 481, James and Mike invite Paul Fritsch to go through all the evidence for the benzoyl peroxide/adapalene and benzoyl peroxide/clindamycin combinations that we use for acne. Call us crazy, but we focus on the important outcome of whether or not the patient thinks the treatment worked. We provide… Read More
In episode 480, James and Mike talk about two recent meta-analyses that have done a solid job of looking at the impact of lowering blood pressure and using SGLT-2s and GLP-1s to reduce risk. Both publications lend credence to the concept of focusing much more on risk reduction goals than… Read More
