n episode 487, Mike and James invite Mike Kolber in to chat about the real-world evidence we have for the COVID vaccine. We find the effectiveness of the COVID vaccines pretty much mirrors what the original clinical trials show. There is also effectiveness evidence the vaccine works for the variants… Read More
In episode 484, Mike and James go PREMIUM on two topics that annoy them – Vitamin D and interpretation of tests. We find there is no value to using Vitamin D to prevent acute respiratory infections and that as health care providers we overestimate the probability of diagnoses before and… Read More
In episode 485, Mike and James go over a couple of COVID trials that show two different anti-inflammatories – colchicine and inhaled budesonide – seem to have an effect on reducing hospitalizations or urgent care visits. 1) Colchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded,… Read More
In episode 483, James and Mike invite Tina to the podcast to talk about the aducanumab (Aduhelm) FDA approval story. We look at all the latest evidence, we talk about how people analyzed the data, whether or not the findings were clinically important, the side effects and finally the cost. Read More
In episode 482, Mike and James take a look into all the evidence for baths for atopic dermatitis. The evidence is fairly clear that more frequent bathing has a reasonable effect in people with moderate to severe atopic dermatitis. However, adding bleach or anything else to the bath doesn’t seem… Read More
