In episode 440, Mike and James yet again invite Adrienne to go over all the evidence for treating toenail onychomycosis. We find that ~ 40% more people get better on oral treatments than on placebo. For topicals the number is closer to 10%. Topicals should likely only be used if… Read More
“The art and science of medication optimization for heart failure with reduced ejection fraction” with Dr. Christine Ryan and Mr. Zack Dumont, in partnership with RxFiles. The learning objectives are: Explain the necessity of guarding against clinical inertia Explore core therapy medication options and implement an approach to management Compare… Read More
In episode 439, Mike and James invite Adrienne to take us through the impressively large amount of evidence for the PDE5 inhibitors for erectile dysfunction. We find that the NNTs are 2-3 for the not clearly defined endpoint of successful intercourse. There is a 20% absolute increase in adverse effects… Read More
In episode 438, Mike and James discuss 4 studies that likely could change what you are doing, or saying to your patients in your practice. Hip replacements – they last longer than you may think, Vitamin D – bigger isn’t better, actinic keratosis – 5-Flurouracil is best, and weight loss… Read More
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