In episode 490, Mike and James invite Tony and Mike to go over the best available evidence for ivermectin. Overall the evidence shows that ivermectin does not improve clinically important outcomes. Unfortunately, much of the evidence for ivermectin is unpublished and some has even been retracted. Show Notes Tools for Practice… Read More
In episode 489, Mike and James invite Adrienne to go over the evidence for weight loss with semaglutide. We find the evidence shows that weight loss is on average roughly 10 kg over the effect of placebo, however this comes at the expense and inconvenience (injection) of the medication and… Read More
In episode 488, Mike and James invite Mike Kolber back again to chat about what the best evidence says around COVID vaccine adverse effects. We discuss all the numbers around common post-dose side effects, anaphylaxis, thrombotic thrombocytopenia and myocarditis. Show Notes Tools for Practice COVID-19 Vaccine Adverse Events… Membership… Read More
n episode 487, Mike and James invite Mike Kolber in to chat about the real-world evidence we have for the COVID vaccine. We find the effectiveness of the COVID vaccines pretty much mirrors what the original clinical trials show. There is also effectiveness evidence the vaccine works for the variants… Read More
In episode 484, Mike and James go PREMIUM on two topics that annoy them – Vitamin D and interpretation of tests. We find there is no value to using Vitamin D to prevent acute respiratory infections and that as health care providers we overestimate the probability of diagnoses before and… Read More
