#259 Unmasking the evidence around masks for healthcare workers
CLINICAL QUESTION
Is there a difference between mask types in preventing viral respiratory infections for healthcare workers?
BOTTOM LINE
In healthcare workers;
- Surgical masks and respirators (N95) appear to provide similar protection against viral infections, with N95 masks having slightly lower, but not statistically different, infection rates in the wearer (~1-2%).
- Cloth masks are less effective than surgical masks (with ~2% more respiratory infections in 4 weeks).
- No randomized controlled trials examined transmission from healthcare workers to others and none examined COVID-19.
- Masks are just one-part of Personal Protective Equipment and transmission precautions.
Reading Tools for Practice Article can earn you MainPro+ Credits
Join NowAlready a CFPCLearn Member? Log in
EVIDENCE
Evidence:
N95 masks (also called respirators) compared to surgical masks (also called medical) in preventing a wide range of viral respiratory tract infections: 4 systematic reviews with 3-6 Randomized Controlled Trials (RCTs) and 3016-9171 patients (95-100% healthcare workers). Most RCTs 5 weeks, largest 12 weeks.1-4
- Largest Meta-Analysis:1
| Healthcare worker condition | N95 Masks | Surgical Masks | Statistical Difference |
| Confirmed Influenza | 5.9% | 6.3% | No |
| Confirmed Viral Respiratory Tract Infection | 5.7% | 8.3% | No |
| Influenza-like Illness | 3.4% | 5.0% | No |
- Other Systematic Reviews found similar.2-4
- One RCT (1441 healthcare workers) examined fit-tested N95 versus nonfit-tested N95: No difference.5
- Issues: Multiple outcomes, not Covid-19, overall low risk of infection, intervention only used during working hours, did not examine healthcare workers transfer to patients, other staff or family.
- Clinical Respiratory Infections: 7.6% cloth versus 4.8% surgical masks (borderline statistically different).
- Influenza-like Illness: 2.3% cloth versus 0.2% surgical masks (statistically different).
- Laboratory confirmed viral infection: 5.5% cloth versus 3.3% surgical mask (not statistically different).
- In general, when blocking particles/droplets/microorganisms, N95 are slightly better than surgical masks which are better than cloth masks (which get better with thicker cloth/layers).4,7,8
- Masks, compared to no masks, do help prevent infections (example ~3.5% reduction in clinical respiratory infections in RCTs).3,9
- Wearing a mask might prevent infected healthcare workers, including asymptomatic individuals, from transmitting the disease to others.
- Masks should not be considered as an isolated intervention and should always be used with other measures such as hand hygiene and depending on interaction and patients seen, eye protection, face shields and gowns.
- Public use of masks will be reviewed in an upcoming Tools for Practice.
Latest Tools for Practice
#363 Making a difference in indifference? Medications for apathy in dementia
In patients with dementia, how safe and effective are stimulants, antidepressants, and antipsychotics for treating apathy?
#362 Facing the Evidence in Acne, Part I: Oral contraceptives and spironolactone in females
How effective are combined oral contraceptives (COC) and spironolactone for treating acne of at least mild-moderate severity in females?
#361 Preventing RSV Infections in Infants
How safe and effective are monoclonal antibodies to prevent respiratory syncytial virus (RSV) infections in infants?
