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#391 Trying Tongue-Tie Treatment: Does Frenotomy Fix Feeding Frustrations?


CLINICAL QUESTION
QUESTION CLINIQUE
Does surgical frenotomy in infants with ankyloglossia (tongue-tie) improve mother or infant breastfeeding outcomes?


BOTTOM LINE
RÉSULTAT FINAL
Surgical frenotomy likely reduces maternal nipple pain ~2 points on a 10-point scale, and “improves breastfeeding” in 78-96% versus 3-47% in control groups. Effects on infant weight gain and rates of breastfeeding are unknown, due to large crossover in control groups. Most common adverse events are bleeding (up to 5%) and repeat frenotomy (up to 4%). 



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EVIDENCE
DONNÉES PROBANTES
  • Results are statistically significant unless otherwise reported.
  • 6 randomized control trials (RCTs), infants 1 day to 10 weeks of age, with ankyloglossia and breastfeeding difficulties (25-169 patients).1-6
    • Nipple pain, comparing pre-frenotomy to post-frenotomy (immediately after procedure and up to 2 weeks):
      • ~2 point improvement on 10-point visual analogue scale.1-4
        • Statistically different in 1 RCT,4 others1-3 statistics not reported.
        • 1 RCT: No statistical difference versus sham.2
      • ~12-point improvement versus 6 (sham) on 50-point scale.5
      • Changes likely clinically relevant.
    • Self-reported breastfeeding improvement, frenotomy versus none,2 sham procedure,5 or “intensive lactation consultation support”.6 At 0-48 hours:
      • 78-96% versus 3-47% (control),2,6 numbers needed to treat (NNT)=1-3.
      • Overall breastfeeding assessment score (15-point scale): Improved 2.3 (frenotomy) versus decreased 0.41 points (sham procedure).5
    • Any breastfeeding, at 3 months of age, as-treated analysis:
      • 90% (frenotomy) versus 69% (breastfeeding support only).1
      • Intention-to-treat analysis uninterpretable (73-85% patients underwent frenotomy in control groups).1,3
    • Adverse events, not statistically different:
      • Minor bleeding: ~1 to 5%.1,2
      • Repeat frenotomy: 4%.3
      • Salivary duct damage: ~1%.1
      • Small white patch at frenulum base: ~64%, healed ~7 days.3
  • Limitations: Long-term outcomes (examples: Infant weight gain, continued breastfeeding) uninterpretable due large numbers of controls undergoing procedure (73% to 100%).1,3 Breastfeeding scores do not always include nipple pain. Largest RCT stopped early due to COVID-19.1 Systematic review unable to pool most results.7

CONTEXT
CONTEXTE
  • Ankyloglossia is a functional diagnosis. Evaluate by observing latch and breastfeeding; appearance of tongue tie alone does not necessitate intervention.8,9
  • Frenotomy only indicated to improve nipple pain and latch difficulties.8,9
  • Surgical frenotomy is considered standard of care over laser.9


Thibaut Spire June 7, 2025

Pas d’étude à haute puissance mettant en évidence une amélioration de la santé des enfants.

Adeola Olajide June 10, 2025

There is no comment on effect on speech. Are there any research to show speech can be affected or is this a myth?

MOHANAD YASEEN June 14, 2025

informative


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Author(s)
Auteur(s)
  • Caitlin Finley MSc MD CCFP
  • Lauren Eastman BMEdSc MD CCFP
  • Meah Nakehk’o BA
  • Adrienne J Lindblad BSP ACPR PharmD

1. Knight M, Ramakrishnan R, Ratushnyak S, et al. Health Technol Assess. 2023 Jul; 27(11):1-73.

2. Berry J, Griffiths M, Westcott C. Breastfeed Med. 2012; Jun;7(3):189-93.

3. Emond A, Ingram J, Johnson D, et al. Arch Dis Child Fetal Neonatal Ed. 2014 May;99(3):F189-95.

4. Dollberg S, Botzer E, Grunis E, et al. J Pediatr Surg. 2006 Sep;41:1598-1600.

5. Buryk M, Bloom D, Shope T. Pediatrics. 2011 Aug;128(2):280-8.

6. Hogan M, Westcott C, Griffiths M. J Paediatr Child Health. 2005 May-Jun;41(5-6):246-50.

7. O’Shea JE, Foster JP, O’Donnell CPF, et al. Cochrane Database Sys Rev. 2017 Mar 11;3(3):CD011065.

8. Anderson J, Pradhu P, Graham E. CMAJ. 2023 Oct 10;195(39):E1349.

9. LeFort Y, Evans A, Livingstone V, et al. Breastfeed Med. 2021 Apr;16(4):278-81.

Authors do not have any conflicts of interest to declare.

Les auteurs n’ont aucun conflit d’intérêts à déclarer.