#102 Coughing up the Data on Croup
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- Significant improvement in croup symptoms at six hours: Number Needed to Treat (NNT) 5 (95% Confidence Interval 3 to 11).
- Similar improvement at 12 and 24 hours.
- Fewer return visits to emergency and/or (re)admissions: NNT 17 (13 to 28).
- Shorter time spent in emergency or hospital: mean difference 12 hours (5 to 19 hours).
- No reported adverse events.
- Change in croup score from baseline at six hours, Standard Mean Difference -0.02 (-0.37 to 0.32).
- Return visits and/or (re)admissions, Risk Ratio 1.04 (0.62 to 1.75).
- Even children with mild croup (croup score <2) benefit from glucocorticoid treatment.2
- Symptom improvement of steroids may be evident in ten minutes, with statistically significant improvement at 30 minutes.3
- A retrospective observational study found reduced hospital and intensive care admission rates, length of stay and intubations when 0.6 mg/kg dexamethasone was introduced and used in the hospital protocol (1980–1995).4 These rates did not change when 0.6mg/kg was replaced by 0.15 mg/kg in 1995.5